GMP Vector Manufacturing Plant for Tissue Engineering

The World’s first GMP Compliant Vector Manufacturing Plant with “Sendai Virus Vector”

Chiyoda executed EPC (Engineering, Procurement and Construction) work for the facility to manufacture clinical use vector*¹ for tissue engineering and gene-drug development for I’ROM Group Co., Ltd./ID Pharma Co., Ltd..

In the field of tissue engineering such as development of iPS cell and gene therapy and gene vaccine drug, this project is to construct the world’s first GMP compliant vector manufacturing plant including “Sendai Virus Vector” based upon the technology of ID Pharma Co., Ltd., a wholly owned subsidiary of I’ROM Group Co., Ltd.

• 1：Vector is a material that delivers curative gene to the specific organ/anatomy and imports the gene into the targeted cell effectively. “Sendai Virus Vector” which is uniquely developed by ID Pharma Co., Ltd. is centered on RNA, completely different from the existing vector technology. Sendai Virus Vector is verified safe through preclinical testing, and has high reliability and track record in the field of gene-drug and bio-drug.
• 2：GMP stands for Good Manufacturing Practice which clarifies the rules and standards for drug manufacturers to comply with to secure the safety of pharmaceuticals. It covers management for operation of manufacturing plant and quality control for products. Ministerial orders by Ministry of Health, Labour and Welfare regulate the GMP in Japan.